A field experiment was conducted to study the effect of integrated nutrient management in sweet orange cv. Mosambi in the farmer's field under central dry zone of Karnataka, India during 2016-17. The experiment was laid out in Randomized block design with eight treatments comprising of inorganic, organic manures ('N' equivalent) and bio-fertilizers replicated thrice. The treatment (T8) comprising 75% RDF + poultry manure (12.5 % N equivalent) + vermicompost (12.5 % N equivalent) and Arka Microbial Consortia (T8) resulted the highest fresh and dry leaf weight (0.58, 0.80, 0.90 g and 0.30, 0.53, 0.55 g respectively), leaf area (29.34, 32.49 and 34.20 cm2, respectively) at 30,60 and 90 days, maximum current season shoot length (69.33 cm), shoot girth (2.54 cm), canopy spread (3.38 m N-S, 3.43 m E-W) were also recorded and yield attributes such as maximum fruit weight (179.51 g), number of fruits per plant (347.32), yield per plant (61.98 kg), yield per hectare (17.23 t/ha) were obtained during the experimentation. The present study revealed that integrated application of organic and inorganic with bio-fertilizer enhances the vegetative growth and also produce sustainable yield of sweet orange cv. Mosambi.