Black pepper (Piper nigrum) is commercially propagated through single node cuttings of runner shoots. The grafting technique of propagation is gaining popularity in order to avoid Phytophtora foot rot. The objective of this experimental trial was to study the varietal response to grafting technique of propagation in black pepper using Piper colubrinum as root stock. Twenty one varieties of black pepper were wedge grafted and planted in the main field after 90 days of grafting using arecanut palm as standard. The growth parameters were observed and recorded at 30 days interval. The result showed that grafted plants had significant difference in plant height, leaf length and leaf breadth. The varieties Panniyur-1 and Panniyur-3 showed maximum plant height, leaf length and leaf breadth. This indicated that the varieties Panniyur-1 and Panniyur-3 show better response for grafting on Piper colubrinum in hill zone of Karnataka. No graft incompatibility or foot rot incidence is recorded during the study period.