Evaluation of certain bio-rational approaches for the management of defoliators in sunflower were undertaken during 2012-13 at Zonal Agricultural Research Station, UAS, Bengaluru. Among different bio-rationals evaluated against defoliators under field conditions showed best bio-rationals Neem seed kernel extract (NSKE) followed by Garlic chilli kerosene extract (GCKE), V-Bt and Bt-Halt treatments compared to panchagavya, Parthenium leaf extract, Spodoptera NPV and Pongamia Seed Kernel Extract (PSKE) treatments. Among the different bio-rationals highest predatory population recorded in V-Bt treatment, whereas in case of chemical treatment profenophos 50 EC least predatory population was recorded. The treatment V-Bt was recorded highest seed yield (3528 kg/ha.), volume weight (55.14 g/100ml) and oil content (37.78%), followed by seed yield of NSKE (3346 kg/ha.) with volume weight (51.13 g/100ml) when compared to the other bio-rational treatments.