Vermicomposting, as micro-enterprise has been used as an effective tool for organic waste management in many geographies who are largely agro-based.However, vermicomposting as one of the methods of generating additional source of income, economic empowerment and assuring sustainable livelihood approach along with the already known environmental benefits has been newly found to be one of the most appropriateenterprises. As a small enterprise it also has that many constraints to produce at the farm level, hence a study was conducted to identify the constraints faced by vermicompost entrepreneurs and to suggest them to boost vermicompost production in Guntur district of Andhra Pradesh. Sixty respondents were randomly selected from twenty seven mandals. The study revealed that lack of awareness regarding improved methods of vermicompost practices, labour availability, adequate quantity of FYM/ compost is not available, lack of remunerative prices for the produce, attack by pests, lack of knowledge on market information, inadequate transport facilities, high cost of initial investment, lack of demand for the product in the market, inadequate marketing facilities, inadequate training facilities, complex process of obtaining loan/ finance, credit is not available at proper time and difficulty in procuring earthworms.