Male annihilation technique disturbs the sex ratio and reduced the chances of mating which results in suppression of population. Cue lure is a parapheromone, which attract the male of fruit fly, Bactrocera cucurbitae (Coquillett). Wood block can be used for impregnation of parapheromone. The present investigations in relation to B. cucurbitae, the major fruit fly infesting bitter gourd and little gourd in middle Gujarat conditions were carried out on male annihilation technique (MAT) which includes evaluation of different woods and solvent for impregnation of cue lure; standardization of size of plywood blocks for impregnation of cue lure; shelf life of cue lure impregnated blocks; evaluation of different trap designs; standardization of placement of trap and; area wide control using cue lure impregnated plywood blocks. For impregnation of cue lure in wood block, Marsava (Marsdenia volubilis Cooke) wood and plywood was found most suitable. For impregnation of cue lure in plywood block, kerosene, ethanol and hexane were found most suitable solvents. The optimum size for impregnation of cue lure in 1.2 cm thick plywood was found to be 3 x 3 cm (9.0 cm2). The plywood block (5 x 5 cm) impregnated with cue lure (ethanol + cue lure + dichlorvos in the ratio of 6:4:1) and sealed air tightly using aluminum foil can be stored for 2 months without significant adverse effect on fly catches and half-life. Green and yellow coloured traps baited with cue lure caught more flies compared to transparent, white, blue, orange, red, ash and black coloured traps. Empty mineral water bottle with 4 entrance holes on the wall and hung in vertical position was found to be an effective trap design to catch and kill B. cucurbitae using cue lure impregnated block. The optimum position of cue lure-baited trap in small gourd orchard to catch the maximum number of B. cucurbitae was just one foot below and at the border of the pendal.