A field experiment was conducted on deep black soil of Main Cotton Research Station, Surat during kharif season of 2005-06 and 2006-07 to study the effect of depth of tillage and land configuration on physico-chemical properties of soil and cotton productivity under South Gujarat condition. The 30 cm depth of tillage (D3) decreased the bulk density (1.44 gcc-1) and increased infiltration rate (0.27 cm/hr) of soil. Whereas, organic carbon content of soil was significantly higher with shallow depth of tillage (10 cm). Based on pooled analysis of the data, the pH of soil (7.28) was significantly reduced, while available nitrogen and phosphorus content were significantly increased with 30 cm depth of tillage in pooled data. The EC and available K2O content of soil did not alter significantly. 30 cm depth of tillage recorded significantly higher seed cotton yield (2500 kg/ha) as compared to 10 cm depth of tillage but at par with 20 cm depth of tillage. The physical and chemical properties of soil as well as seed cotton yield were found non-significant due to land configuration techniques, except bulk density of soil, which lowered down with ridge and furrow technique in pooled analysis.