Impact of organic manures on growth, yield and nutrient quality of most commonly cultivated vegetable crops like tomato (Lycopersicon esculentum) was investigated at field level. The results revealed that amendment of organic manures like Neem cake and Jeevamrutha found to be highly significant to improve growth and yield attributes. The nutrient quality analysed indicated superiority of organically grown tomato in total carbohydrates, proteins and vitamin C. Along with this soil micro flora and availability of essential nutrients to the plant was also enhanced. This study confirmed the economic profitability as well as sustainable cultivation of tomato, providing better yield and safe vegetables for consumers, maintaining the soil fertility and avoiding the environmental pollution when grown organically.