The effect of different post-harvest treatments on physical and biochemical changes on fruits of mango (Mangifera indica) varieties, such as Alphonso and Bangalora were studied during storage under both ambient and cold storage conditions. The post-harvest treatments given were hot water dip, hydro cooling, sanitization with sodium hypochlorite solution, ozonisation, waxing and dipping in sodium bicarbonate solution. Among the different treatments, 1 per cent Nipro fresh Natural MTS-40 (Carnauba wax) coated fruits stored under cold storage at 12±20C recorded good quality attributes. Coated fruits of Alphonso maintained quality evidenced by reduction in PLW (6.52 %), delayed colour change (16 days), lowest acidity (0.21%), highest total sugar (13.90 %) and non-reducing sugar (12.10 %) with higher TSS (170 brix), firmness (0.09 N), ascorbic acid (49.50mg/ 100g)and total carotenoid (7.80mg/100g), even after a storage period of 23 days under cold storage. Fruits of Bangalora coated with wax had extended shelf life up to 26.50 days against control fruits (17.50days) with lowest PLW (7.80 %), delayed colour change (26 days), lowest acidity (0.10%), firmness (0.32 N), ascorbic acid (9.95 mg/100g), total sugar (7.86%) and TSS of 110 brix.