The study was conducted to asses the effect of supplementing probiotics (multi strain) on growth performance of indigenous calves. Sixteen indigenous calves selected on the basis nearness to age and body weight. They were randomly allotted to four treatment viz., T1 : control (without probiotics), T2 : 5 gm multi strain probiotics per kg concentrate, T3 : 10 gm multi strain probiotics per kg concentrate and T4;15 gm multi strain probiotics per kg concentrate was fed to the indigenous calves. Observation on the body weight gain showed the significant (p< 0.05) differences among the mean values of treatments. The indigenous calves fed under treatments T4 showed higher average daily weight gain 0.476 kg over the other treatments. Whereas the lowest average daily weight gain was recorded under treatments T1 i.e. control group 0.375 kg. A similar trend was observed in the body measurement viz., body length, height and chest girth also shows significant (p < 0.05) difference among the treatments means. The indigenous calves fed under treatment T4 showed higher average body length, height and chest girth over the other treatments. The observation on the water intake and dry matter intake showed significantly (p< 0.05) among the treatments i.e. higher in T4 treatments and lower in T1 (control treatments).The maximum growth rate per kg weight gain of indigenous calves obtained on feeding of multistrain probiotics at lower cost.