Representative samples of water cabbage (L. flava), coirpith, water hyacinth (E. crassipes), and farm wastes (dried leaves and pseudostem of banana) were collected and analysed for bio-chemical composition. Water cabbage recorded 2.74 per cent N, 0.30 per cent P, 0.33 per cent K, 16.98 C:N ratio, and no detectable levels of heavy metals except Ni (0.55 ppm) and inferred as the best substrate in terms of nutrient content followed by water hyacinth, farm wastes and coir pith respectively. The substrates were converted to composts using various inoculants viz. T. reesei, P. sajor-caju, Composting inoculum and commercial enzyme cocktail (cellulase/pectinase and laccase) and physico- chemical and biological characteristics were analyzed. A mixture of (water cabbage + Composting Inoculum) was concluded as the best in terms of nitrogen content, cellulase activity, maturity period, C:N ratio and no detectable levels of heavy metals except Ni (0.414 ppm) followed by the mixture of water hyacinth and Composting inoculum had comparable N, P, K, EC , C:N ratio, and heavy metal content below the detectable limit. Considering the effect of inoculants on different substrates, composting inoculum was concluded as the best in terms of moisture content, EC,N, P, K, dehydrogenase activity, cellulase activity, maturity period and C:N ratio. With regards to inoculants used on different substrates, composting inoculum was found to be the most effective for composting the agrowastes.