Field experiments to capture all the multi-year and multi-location variability are nearly impossible. Under these circumstances, crop simulation models have been emerged as an artistic tool for agronomic management strategy evaluation. The experiment was conducted during kharif, 2013 at Professor Jayshankar Telangana State Agricultural University in Rajendranagar, Hyderabad with three plant densities 60x25 cm (66,666 plants ha-1), 45x25 cm (88,888 plants ha-1) and 45x20 cm (1,11,111 plants ha-1) as factor one and four nitrogen levels (120 kg ha-1, 180 kg ha-1, 240 kg ha-1 and 300 kg ha-1) as factor two to validate the CERES- Maize model in semiarid tropics of Telangana State. Evaluation of CERES-Maize model confirmed that simulation of LAI, phenology, biomass and grain yield was considered as excellent with NRMSE value being less than 10%. But, simulation of number of grains cob-1 and nitrogen uptake by maize grain was good as the NRMSE value was ranged in between 10.1 to 20%. So the model can be used as a research tool in the variable agro-environments of Telangana to suggest suitable planting density and optimum nitrogen level.