The nutritional quality of finger millet genotypes in relation to the physico-chemical properties of soil ,the application of organic manures and inorganic fertilizers was studied. The surface soil (0-15 cm) before sowing (initial) and after harvest of the crop and the grain samples were collected from farmers' fields cultivating white (Dapoli Safed-1) and brown (Dapoli-1) finger millet genotypes, with the application of organic manures and inorganic fertilizers, in Konkan region of Maharashtra state. The soil and grain samples were analysed by following standard analytical methods. In general, soil was sandy clay loam in texture, moderately acidic in reaction, with high organic carbon content and low electrical conductivity. The availability of N was medium, P was low, K status was high. DTPA extractable micronutrients (Fe, Mn, Zn and Cu) were found to be adequate. The physico-chemical properties of soil represented the typical lateritic soils of Konkan region. There was depletion in available macro and micronutrient status after harvest of the crop as compared to initial status. Organic manure application showed significant positive effect on available nutrient status of N, P, Fe and Zn in brown genotype and with P, Fe and Mn in white genotype. When nutritional qualities of Brown and White genotypes were compared, white finger millet showed significantly higher content of protein, crude fibre, Fe, Mn and Zn, whereas carbohydrate, energy, Ca and P contents were significantly higher in Brown finger millet. Further, organic manure application showed significant positive correlation with yield, protein, energy and P. The physico-chemical properties of soil showed significant effect on the nutritional quality of finger millet.