Experiment was conducted on rice (Oryza sativa) during kharif 2015 at Instructional Farm of Krishi Vigyan Kendra, Raigarh (C.G.) to investigate the yield limiting nutrients through crop response in Vertisols with rice (MTU-1010) as test crop. The experiment was laid out in Completely Randomized Design (CRD) with 11 treatments and 3 replications. Yield attributing characters viz., effective tillers, filled grains panicle-1 and grain and straw yields of rice significantly influenced by nutrient omission treatments. Omission of N, P, S and Zn resulted in significant reductions in yield attributing parameters and grain and straw yields. Highest grain and straw yields (28.69 and 31.35 g pot-1, respectively) were recorded with the treatment receiving all the nutrients whereas the lowest with omission of N (18.46 and 21.01 g pot-1, respectively) followed by P, S and Zn omission. Omission of N reduced the grain yield by 35.65% while P omission reduced grain yield by 28.89% over the treatment receiving all nutrients. omission of N, P and S reduced the yield attributing parameters and grain and straw yields significantly. Nutrient uptake by rice was significantly reduced with omission of N, P, S and Zn. On the basis of per cent grain yield reduction, the limiting nutrients found in the order of N > P > S > Zn.