The present paper aims to study on eco restoration and natural resource management base for sustainable rural livelihood in Andhra Pradesh. The results reveals that, in Anantapur district mandal and district wise impact of Eco-restoration and regeneration of natural resource base for sustainable livelihood was studied in Anantapur district. It was found that in Anantapur district there was increase in ground water levels after the implementation of MGNREGS in all the three mandals. The increase was highest (11.43 per cent) in Mudhigubba mandal. However in all the 3 mandals the increase was found to be significant as indicated by the't' values. The increase in irrigated area was also highest in Mudhigubba mandal and it was found to be 15.16 per cent. There was significant increase in plantation crops area and the increase was highest (280 per cent) in Kanaganapalli mandal. Community land development nature of work and area was found to be more in Kalyandhurg mandal and the increase (133.8 per cent) was found to be significant as indicated by the't' value. However, in overall situation it was 78.33 per cent expressed there was overall increase in agriculture productivity while 52.78 while per cent of respondents perceived that there was no change in availability of irrigation / drinking facility. Majority of the respondents opined an increase in opportunity in soil and water conservation (51.67 per cent), water table of the area (72.28 per cent), flood control and protection (57.78 per cent) and land development (72.22 per cent). About 72.22 per cent respondents agreed that due to MGNREGS there was overall development in their villages.