Rice (Oryza sativa L.) is the prime staple food in many countries of the world. Zinc deficiency is the major micronutrient problem in rice and it leads to “Khaira” disease. Present investigation was taken to screen and understand the response of recombinant inbred lines in field condition and nutrient solution for zinc deficiency tolerance which may helpful to standardize screening protocols for zinc deficiency tolerance in rice. Phenotypic data generated under rainfed zinc deficiency field condition at research-cum instructional farm of COA, IGKV, Raipur using 271 recombinant inbred lines(RILs) derived from cross between two indica genotypes, Danteshwari and Dagad Deshi during wet season 2011 and finally extreme tolerant and susceptible lines were selected to screen in nutrient solution. Reaction of extreme susceptible and tolerant lines under field condition did not matched with the screened result of same lines grown in modified Yoshida nutrient solution without zinc nutrient under controlled glass house. This may be due to difference in establishment of rhizosphere in field condition and nutrient solution, combining of stress factors along with zinc deficiency in development of bronze leaf symptoms, difference in pH of the solution and field condition and remobilization of nutrients.