Nutrient stress is one of the most important factors for lower productivity of sesame and the low average yield of the crop might be due to cultivation of low yielding traditional varieties and poor management practices of planting system. The experiment was carried out at Crop research field of SHIATS, Deemed University, Allahabad. To study the influence of different planting systems and varieties through organic management practices on yield attributes and yield of sesame (Sesamum indicum L.) during the kharif season 2010-11. Experiment comprised of three planting systems, viz., (M1) raised bed, (M2) ridge and furrow and (M3) flat bed, three varieties, viz., (V1) A KT 8, (V2) Madhuri and (V3) Gujarat 1 and organic manures, viz., (O1) farm yard manure and (O2) neem cake. The study revealed that planting system ridge and furrow system registered significantly higher seed yield (562.12 kg ha-1) over raised bed and flat bed planting system. Application of organic manure in the form of neem cake has recorded significantly higher seed yield (537.59 kg ha-1) over the farm yard manure. Among the varieties Madhuri (613.56 kg ha-1) had recorded significantly higher seed yield and yield attributes. Interaction effects were found significant for yield and yield attributes.